St. Andrew's is located at 5801 Hampton Street, one block south of Bryant Street and four blocks south of the Park,  in the East End Pittsburgh neighborhood Highland Park.

From Route 28 take Exit 6, the Highland Park Bridge, exiting right toward Butler Street.  Turn left at the first stoplight, "One Wild Place," and continue approximately 3/4 of a mile to the "Zoo Mural," where the road divides.  Turn right, and then take the first left turn onto Bunkerhill Avenue.  Continue two blocks to N. Euclid Avenue.  Turn right and continue four blocks.  Church stands at the corner of Hampton Street and North Euclid Avenues.

From Route 376, the Parkway East, take the Wilkinsburg  Exit and continue west on Penn Avenue through Wilkinsburg into Pittsburgh.  At North Highland Avenue turn right and continue north on North Highland Avenue three blocks past the stoplight at Stanton Avenue.  Turn left on Hampton Street and continue one block.  

From locations within the City take Fifth Avenue to Negley Avenue, then Negley Avenue north through Shadyside and East Liberty into Highland Park.  Hampton Street is three blocks past the stoplight at Stanton Avenue.  Turn right at stop sign and continue two blocks.  Church will be on your left, just past Fulton Elementary School.